one minute cures regarding hydrogen peroxide

Dermal: Localised listening or even skin necrosis can occur.If high concentrations are inhaled it is possible to develop severe respiratory distress, coma, seizures and pulmonary oedema. Inhalation: Coughing and transient dyspnoea.Features of gas emboli include hemiplegia, altered GCS, blindness, focal motor or sensory signs, multifocal neurological deficit or cardiac arrhythmias.

Ingestion: ranges from the symptoms associated with GI irritation (nausea, vomiting, haematemasis, foaming at the mouth) to upper airway distress (oral burns, laryngospasm, stridor, cyanosis and respiratory arrest) to severe toxicity form the 10% solutions (tachycardia, confusion, coma, seizures, cardiac arrest and death).

Any higher concentration or if they have symptoms warrants hospital evaluation.

Children: minor exposures to solutions 3% of less are unlikely to cause significant injury.

If exposed to the cornea it can cause permanent injury.

Ingestion of small volumes (10% ingestions can cause potentially life-threatening corrosive injury to the airway, GI tract and propagate life-threatening gas emboli.

Hypotension: Usually responds to fluid administration, noradrenaline is second line therapy, other vasopressors may be used.

Hyperbaric oxygen maybe required to all those with symptoms of cerebral gas embolism.

Airway compromise: Intubate and ventilate especially if signs of laryngeal oedema (stridor, dysphonia, throat pain, horseless or respiratory distress).

35 ml of 35% hydrogen peroxide liberates 3.5L of oxygen at a standard pressure and temperature.

Rapidly metabolised – predominantly by red cells to yield oxygen and water.

Lipid per oxidation causes direct cytotoxic effects. If foaming occurs in the left ventricle then cardiac output can be severely impeded. If oxygen forms i na hollow viscus under tension then perforation is possible. Once solubility in the blood is at maximum oxygen will precipitate in the venous and arterial circulation to form gas emboli. Metabolism of hydrogen peroxide will liberate large quantities of oxygen. Hydrogen peroxide is corrosive and exposure causes local tissue damage. One tox email circulated during my clinical attachment of a patient who ingested hydrogen peroxide, seemed fine and then boarded a plane to develop the “bends” from oxygen formation and improve some what during landing. It causes damage by three main mechanisms: direct corrosive injury, oxygen gas formation and lipid peroxidation. Hydrogen Peroxide is an oxidising agent used widely in domestic and industrial products.

One minute cures regarding hydrogen peroxide